--- title: Towards Transformative Therapies for Sickle Cell Disease description: "New York Academy of Sciences\nSickle Cell Disease\nConferences" image: https://www.functionalfluidics.com/hubfs/shutterstock_533072995.jpg --- [![functionalfluidics_logo](https://www.functionalfluidics.com/hs-fs/hubfs/functionalfluidics_logo.jpg?width=132&name=functionalfluidics_logo.jpg)](https://www.functionalfluidics.com/) - [About Us](https://www.functionalfluidics.com/about-us) - [Services](https://www.functionalfluidics.com/services) - [Assays](https://www.functionalfluidics.com/assays-2) - [Flow Adhesion](https://www.functionalfluidics.com/assays/flow-adhesion) - [Mechanical Fragility](https://www.functionalfluidics.com/assays/mechanical-fragility) - [Dynamic Sickling Assay](https://www.functionalfluidics.com/assays-dynamicsicklingassay) - [Oxygenscan](https://www.functionalfluidics.com/assays/lorrca-oxygenscan) - [Osmoscan](https://www.functionalfluidics.com/assays-2/flow-adhesion-reverse-0) - [Contract Research](https://www.functionalfluidics.com/contractresearch) - [Nigeria Research Center](https://www.functionalfluidics.com/functional_fluidics_nigeria) - [RBC Test Menu](https://www.functionalfluidics.com/hubfs/Test%20Menu%20(2).pdf) - Scientific Resources - [Peer Reviewed Publications](https://www.functionalfluidics.com/scientificresources/peerreviewed) - [Abstracts](https://www.functionalfluidics.com/scientificresources/abstracts) - [ELIPSIS](https://www.functionalfluidics.com/scientificresources/elipsis) - [News](https://www.functionalfluidics.com/news-and-presentations) [< Go Back To News & Media](https://www-functionalfluidics-com.sandbox.hs-sites.com/news-and-presentations/) ## Towards Transformative Therapies for Sickle Cell Disease Towards Transformative Therapies for Sickle Cell Disease - - - October 24, 2017 0% read Subscribe to our Newsletter ## ![shutterstock_533072995](https://www.functionalfluidics.com/hs-fs/hubfs/shutterstock_533072995.jpg?width=600&name=shutterstock_533072995.jpg) ### Functional Fluidics was honored to participate in this event organized by The New York Academy of Sciences in October of 2017: [![Screenshot 2018-03-06 18.09.25.png](https://www.functionalfluidics.com/hs-fs/hubfs/Screenshot%202018-03-06%2018.09.25.png?width=1113&name=Screenshot%202018-03-06%2018.09.25.png)](https://www.nyas.org/ebriefings/2018/towards-transformative-therapies-for-sickle-cell-disease/?tab=overview) Born with sickle cell disease (SCD), a blood disorder marked by frequent vaso-occlusive crises (VOC) in which patients experience fatigue and extreme pain. These crises can lead to organ damage and in the long term, early mortality. To date, the FDA has only approved two treatments for the disease. But improved insight into the complex pathophysiology of SCD has led to the recent development of diverse approaches for treatment, including inhibition of hemoglobin polymerization, prevention and treatment of vaso-occlusive events, and disease corrective gene therapy approaches. On October 24, 2017, the New York Academy of Sciences and the Biochemical Pharmacology Discussion Group presented [Towards Transformative Therapies for Sickle Cell Disease](https://www.nyas.org/events/2017/towards-transformative-therapies-for-sickle-cell-disease/). The event brought together leading researchers and scientists from across the field to discuss key biological mechanisms of the disease and innovative new approaches for treatment, while underscoring the importance of the patient experience. [The meeting report is available free for members by following this link](http://Overview%20Every%20year,%20more%20than%20300,000%20people%20are%20born%20with%20sickle%20cell%20disease%20(SCD),%20a%20blood%20disorder%20marked%20by%20frequent%20vaso-occlusive%20crises%20(VOC)%20in%20which%20patients%20experience%20fatigue%20and%20extreme%20pain.%20These%20crises%20can%20lead%20to%20organ%20damage%20and%20in%20the%20long%20term,%20early%20mortality.%20To%20date,%20the%20FDA%20has%20only%20approved%20two%20treatments%20for%20the%20disease.%20But%20improved%20insight%20into%20the%20complex%20pathophysiology%20of%20SCD%20has%20led%20to%20the%20recent%20development%20of%20diverse%20approaches%20for%20treatment,%20including%20inhibition%20of%20hemoglobin%20polymerization,%20prevention%20and%20treatment%20of%20vaso-occlusive%20events,%20and%20disease%20corrective%20gene%20therapy%20approaches.%20%20On%20October%2024,%202017,%20the%20New%20York%20Academy%20of%20Sciences%20and%20the%20Biochemical%20Pharmacology%20Discussion%20Group%20presented%20Towards%20Transformative%20Therapies%20for%20Sickle%20Cell%20Disease.%20The%20event%20brought%20together%20leading%20researchers%20and%20scientists%20from%20across%20the%20field%20to%20discuss%20key%20biological%20mechanisms%20of%20the%20disease%20and%20innovative%20new%20approaches%20for%20treatment,%20while%20underscoring%20the%20importance%20of%20the%20patient%20experience.)   Subscribe to our Newsletter Subscribe to our Newsletter ### ### Recommended Reads ![](https://www.functionalfluidics.com/hubfs/Screenshot%202025-12-01%20105529.png) Dec 1, 2025 #### [Functional Fluidics Welcomes Biopharma Leader Bert Bruce as Senior Advisor](https://www.functionalfluidics.com/publications/functional-fluidics-welcomes-biopharma-leader-bert-bruce-as-senior-advisor) ![](https://www.functionalfluidics.com/hubfs/Screenshot%202025-11-30%20195918.png) Dec 1, 2025 #### [Functional Fluidics to Present New Sickle Cell Disease Data at the 2025 ASH Annual Meeting in Orlando, Florida](https://www.functionalfluidics.com/publications/functional-fluidics-to-present-new-sickle-cell-disease-data-at-the-2025-ash-annual-meeting-in-orlando-florida) ### Contact Us   # **Our Location** 440 Burroughs Street, Suite 447, Detroit, MI 48202 United States Email: [info@functionalfluidics.com](mailto:info@functionalfluidics.com) Phone:313-315-2555 ### Subscribe to Our Newsletter - [Services](https://www.functionalfluidics.com/services) - [Assays](https://www.functionalfluidics.com/assays-2) - [RBC Test Menu](https://www.functionalfluidics.com/hubfs/Test%20Menu%20(2).pdf) - [Publications](https://www.functionalfluidics.com/publications/tag/publications) © Copyright Functional Fluidics 2016.